2014 - Volume 2 - Issue 1 Articles
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Case Report | ArticleJune 19, 2014 | Pages : 205 - 450Abstract Ischemic stroke following snake bite is rare. We report a case of a 45 years old female developing hemorrhagic manifestations and left sided hemi paresis following a snake bite (unknown species). MRI brain shows multiple acute brain infarct/ toxic le.....
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Editorial | ArticleBy A. Shaver A. Gardner A. Yenamandra D. Zalepa F.C. Wheeler J. Douds M. Guanchez-Lopez M.A. Thompson S. MohanJanuary 16, 2014 | Pages : 205 - 450Abstract Rare de novo AML and MDS in male patients has been reported in a few cases with massive hyperdiploid and tetraploid karyotype [1-3]. A low remission rate and short survival are characteristic of this prognostically unfavorable cytogenetic group in de.....
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Research Article | ArticleJanuary 15, 2014 | Pages : 205 - 450Abstract G2E3 is a G2/M-specific gene that is down-regulated in response to DNA damage. It is highly regulated at both the transcriptional and post-translational levels. It plays a critical role in early embryonic development, as murine G2E3-deficient blastul.....
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Review Article | ArticleJanuary 16, 2014 | Pages : 205 - 450Abstract Arming antibodies with potent cytotoxic drugs greatly enhances the activity of antibodies, while reduces the systemic toxicity of cytotoxic drugs. Resent approvals of antibody-drug conjugates (ADCs) by FDA and the good performance of ADCs in clinical.....
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Mini Review | ArticleJune 19, 2014 | Pages : 205 - 450Abstract First described in 1972 by Benveniste and colleagues, platelet-activating factor (PAF) remains one of the potent phospholipid known to date. The role of PAF produced enzymatically in mediating diverse biological and pathophysiological processes inclu.....